(S)-3-hydroxytetradecanoyl-CoA is a long-chain (3S)-hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (S)-3-hydroxytetradecanoic acid. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a myristoyl-CoA and a (S)-3-hydroxytetradecanoic acid. It is a conjugate acid of a (S)-3-hydroxytetradecanoyl-CoA(4-).;(S)-3-Hydroxytetradecanoyl-CoA is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).;(S)-3-Hydroxytetradecanoyl-CoA is a natural product found in Homo sapiens with data available.;(S)-3-hydroxytetradecanoyl-CoA is a metabolite found in or produced by Saccharomyces cerevisiae.