凯库乐欢迎您! 17558870519
工作时间【周一至周五 9点-17点】 English
您当前的位置:
Malonyl-CoA (Synonyms:S-(hydrogen malonyl)coenzyme A;Malonyl coenzyme A;Coenzyme A, S-(hydrogen propanedioate))
目录号 : FMC0003 纯度 : BR/95%以上 品牌 : CHEMSOON Cas No. : 524-14-1 PubChem Id : 644066
Omega-carboxyacyl-CoA is an acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of any alpha,omega-dicarboxylic acid. It is functionally related to an alpha,omega-dicarboxylic acid. It is a conjugate acid of an omega-carboxyacyl-CoA(5-).
Malonyl-CoA
Cas No. : 524-14-1
规格编号 纯度 包装 库存 价格 拼团价
FMC0003-2mg BR/95%以上 2mg
面议
FMC0003-5mg BR/95%以上 5mg
面议
产品名称: Malonyl-CoA
其他名称: S-(hydrogen malonyl)coenzyme A;Malonyl coenzyme A;Coenzyme A, S-(hydrogen propanedioate)
CAS:524-14-1
结构信息
分子式 C24H38N7O19P3S 分子量 853.58
IUPAC Name  S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] 3-hydroxy-2-methylbutanethioate
InChIKey  PEKYNTFSOBAABV-UHFFFAOYSA-N
InChI  InChI=1S/C26H44N7O18P3S/c1-13(14(2)34)25(39)55-8-7-28-16(35)5-6-29-23(38)20(37)26(3,4)10-48-54(45,46)51-53(43,44)47-9-15-19(50-52(40,41)42)18(36)24(49-15)33-12-32-17-21(27)30-11-31-22(17)33/h11-15,18-20,24,34,36-37H,5-10H2,1-4H3,(H,28,35)(H,29,38)(H,43,44)(H,45,46)(H2,27,30,31)(H2,40,41,42)
SMILES  CC(C(C)O)C(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O
相关文献

1.One-Pot Enzymatic Total Synthesis of Presteffimycinone, an Early Intermediate of the Anthracycline Antibiotic Steffimycin Biosynthesis. Wang, Guojun et al. Organic Letters, 19(3), 540-543; 2017

2.Biocatalytic Total Synthesis of Ikarugamycin. Greunke, Christian et al. Angewandte Chemie, International Edition, 56(15), 4351-4355; 2017

3.Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis. Zhang, Lihan et al. Angewandte Chemie, International Edition, 54(45), 13462-13465; 2015

4.Evaluating nonpolar surface area and liquid chromatography/mass spectrometry response: an application for site occupancy measurements for enzyme intermediates in polyketide biosynthesis. Randall, Shan M. et al. Rapid Communications in Mass Spectrometry, 28(23), 2511-2522; 2014

5.Rapid preparation of (methyl)malonyl coenzyme A and enzymatic formation of unusual polyketides by type III polyketide synthase from Aquilaria sinensis. Gao, Bo-Wen et al. Bioorganic & Medicinal Chemistry Letters, 25(6), 1279-1283; 2015

6.Promiscuity of a modular polyketide synthase towards natural and non-natural extender units. Koryakina, Irina et al. Organic & Biomolecular Chemistry, 11(27), 4449-4458; 2013

7.Enzymatic Extender Unit Generation for In Vitro Polyketide Synthase Reactions: Structural and Functional Showcasing of Streptomyces coelicolor MatB. Hughes, Amanda J. and Keatinge-Clay, Adrian. Chemistry & Biology (Cambridge, MA, United States), 18(2), 165-176; 2011

8.Enzymatic Total Synthesis of Rabelomycin, an Angucycline Group Antibiotic. Kharel, Madan Kumar et al. Organic Letters, 12(12), 2814-2817; 2010

9.Enhancing the Atom Economy of Polyketide Biosynthetic Processes through Metabolic Engineering. Lombo, Felipe et al. Biotechnology Progress, 17(4), 612-617; 2001